Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Wnt4
Flybase description The gene Wnt oncogene analog 4 is referred to in FlyBase by the symbol Dmel\Wnt4 (CG4698, FBgn0010453).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -34.0091 -14.4369 -30.327503 -32.5786 -46.132543 -22.3664 -26.4088 -28.241171
    Affimetrix absolute value 3.346 3.793 3.273 3.375 3.241 4.08 3.831 3.478
    Affymetric present call in "x" number of chips 0 1 0 1 1 3 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: female gonad development; establishment of imaginal disc-derived wing hair orientation; non-canonical Wnt receptor signaling pathway; retinal ganglion cell axon guidance; cell migration; neural retina development; salivary gland morphogenesis; Wnt receptor signaling pathway, planar cell polarity pathway.
18 alleles are reported.
The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system; organ system subdivision; adult segment; external compound sense organ; nervous system; peripheral nervous system; non-connected developing system; multi-cell-component structure; adult mesothoracic segment; germarium; abdominal segment 7; female germline cyst; abdominal segment 8; abdominal segment 10; wing hair; embryonic foregut.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Secreted growth factor Wnt protein, conserved site; Wnt.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages.