Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tutl
Flybase description The gene turtle is referred to in FlyBase by the symbol Dmel\tutl (CG15427, FBgn0010473).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -55.0578 -27.7197 -38.316782 -42.9149 -61.274971 -55.3223 -64.93436 -40.97069
    Affimetrix absolute value 2.663 2.835 2.932 2.98 2.832 2.775 2.534 2.947
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: regulation of dendrite morphogenesis; dendrite self-avoidance; larval behavior; axon guidance; axonal defasciculation; lateral inhibition; adult locomotory behavior; flight behavior; axon midline choice point recognition.
29 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; nervous system; adult segment; commissure; peripheral nervous system; presumptive embryonic/larval nervous system; tract neuropil; external compound sense organ; adult brain.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin V-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.