Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name lwr
Flybase description The gene lesswright is referred to in FlyBase by the symbol Dmel\lwr (CG3018, FBgn0010602).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.284 2.1915 1.584635 1.2973 -0.513912 0.4849 1.20471 0.541741
    Affimetrix absolute value 8.76 8.733 8.805 8.75 8.538 8.756 8.814 8.478
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; SUMO ligase activity; heat shock protein binding.
There is experimental evidence for 14 unique biological process terms, many of which group under: biological regulation; cell cycle; macromolecule modification; immune system process; M phase of meiotic cell cycle; protein modification process; cell cycle process; regulation of developmental process; cellular macromolecule metabolic process; multicellular organismal process.
26 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; organ system subdivision; adult segment; thoracic segment; embryonic/larval hemocoel; embryonic segment; portion of tissue; embryonic head; embryonic/larval fat body; podocyte; adult; external compound sense organ.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.