Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sec61beta
Flybase description The gene Sec61β is referred to in FlyBase by the symbol Dmel\Sec61β (CG10130, FBgn0010638).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.9271 15.577 13.392278 6.1752 6.292756 5.4622 3.91076 9.304528
    Affimetrix absolute value 10.708 11.551 11.879 11.007 11.4 11.01 10.499 11.415
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein transporter activity.
There is experimental evidence that it is involved in the biological process: negative regulation of autophagy.
16 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; leg; chorion; embryonic/larval trachea; egg; dorsal appendage; denticle belt.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Preprotein translocase Sec, Sec61-beta subunit; Preprotein translocase Sec, Sec61-beta subunit, eukarya.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.