Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sqz
Flybase description The gene squeeze is referred to in FlyBase by the symbol Dmel\sqz (CG5557, FBgn0010768).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -45.7188 -23.9157 -43.706538 -55.1108 -60.782353 -46.665 -66.46848 -49.263603
    Affimetrix absolute value 2.91 3.085 2.74 2.646 2.86 3.034 2.5 2.663
    Affymetric present call in "x" number of chips 1 3 1 2 0 1 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: dendrite morphogenesis; neuron development; muscle organ development; oogenesis; neuroblast development; dendrite guidance.
18 alleles are reported.
The phenotypes of these alleles are annotated with: ventral nerve cord commissure; proboscis; ventral nerve cord; tarsal segment; longitudinal connective; wing; dorsal appendage; embryonic/larval neuron; embryonic/larval muscle system; wing hinge.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in adult female stages.