Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name l(3)02640
Flybase description The gene lethal (3) 02640 is referred to in FlyBase by the symbol Dmel\l(3)02640 (CG9165, FBgn0010786).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.2756 -11.7608 -14.805408 -20.5045 -27.778549 -27.3053 -18.84997 -16.053727
    Affimetrix absolute value 4.163 4.108 4.322 4.04 3.994 3.797 4.317 4.296
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: hydroxymethylbilane synthase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: peptidyl-pyrromethane cofactor linkage; tetrapyrrole biosynthetic process.
19 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, N-terminal; Porphobilinogen deaminase, dipyrromethane cofactor binding site; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.