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|Flybase description||The gene hephaestus is referred to in FlyBase by the symbol Dmel\heph (CG31000, FBgn0011224).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding.
There is experimental evidence that it is involved in the biological process: spermatid development; imaginal disc-derived wing margin morphogenesis; sperm individualization; oocyte microtubule cytoskeleton polarization; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; negative regulation of oskar mRNA translation.
113 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; elongation stage spermatid; macrochaeta; testis; mesothoracic tergum; wing; spermatid cyst; individualization stage spermatid; spermatozoon.
It has 24 annotated transcripts and 24 annotated polypeptides.
Protein features are: HnRNP-L/PTB/hephaestus splicing factor; Nucleotide-binding, alpha-beta plait; RNA recognition motif domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.