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|Flybase description||The gene ken and barbie is referred to in FlyBase by the symbol Dmel\ken (CG5575, FBgn0011236).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; nucleic acid binding.
There is experimental evidence that it is involved in the biological process: imaginal disc-derived female genitalia development; female analia development; male analia development; insemination; imaginal disc-derived male genitalia development; regulation of JAK-STAT cascade; phagocytosis, engulfment.
29 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; organ system; region of integument; adult segment; adult; antennal segment; larval abdominal segment; spiracle; vagina; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 12-18 embryonic stages.