Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name ken
Flybase description The gene ken and barbie is referred to in FlyBase by the symbol Dmel\ken (CG5575, FBgn0011236).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.3953 -2.7033 -5.90585 -6.4765 -12.818655 -8.7443 -4.86367 -9.443882
    Affimetrix absolute value 5.987 6.197 5.689 5.736 5.102 5.449 6.3 5.173
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; nucleic acid binding.
There is experimental evidence that it is involved in the biological process: imaginal disc-derived female genitalia development; female analia development; male analia development; insemination; imaginal disc-derived male genitalia development; regulation of JAK-STAT cascade; phagocytosis, engulfment.
29 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; organ system; region of integument; adult segment; adult; antennal segment; larval abdominal segment; spiracle; vagina; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 12-18 embryonic stages.