Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fzo
Flybase description The gene fuzzy onions is referred to in FlyBase by the symbol Dmel\fzo (CG4568, FBgn0011596).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -36.6726 -19.4234 -29.950527 -31.8208 -48.437334 -27.957 -29.77822 -34.364558
    Affimetrix absolute value 3.217 3.368 3.363 3.418 3.215 3.771 3.664 3.196
    Affymetric present call in "x" number of chips 0 1 1 1 1 2 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence that it is involved in the biological process: sperm mitochondrion organization; Nebenkern assembly; mitochondrial fusion; mitochondrion organization.
9 alleles are reported.
The phenotypes of these alleles are annotated with: Nebenkern; Nebenkern derivative; spermatid.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Dynamin, GTPase domain; Fzo/mitofusin HR2 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period, in adult male stages.