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|Flybase description||The gene Imitation SWI is referred to in FlyBase by the symbol Dmel\Iswi (CG8625, FBgn0011604).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; nucleosome-dependent ATPase activity; DNA-dependent ATPase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: cellular component organization or biogenesis; biological regulation; chromatin organization; organelle organization; anatomical structure development; cellular macromolecular complex subunit organization; regulation of cellular macromolecule biosynthetic process; regulation of biological process; gene expression; chromosome organization.
18 alleles are reported.
The phenotypes of these alleles are annotated with: eye; wing disc; mechanosensory chaeta; polytene chromosome; dorsocentral bristle; euchromatin; mesothoracic tergum; condensed chromosome.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: ATPase, nucleosome remodelling ISWI, HAND domain; DEAD-like helicase; Helicase, C-terminal; Homeodomain-like; SANT domain, DNA binding; SANT, eukarya; SLIDE; SNF2-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.