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|Flybase description||The gene La autoantigen-like is referred to in FlyBase by the symbol Dmel\La (CG10922, FBgn0011638).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 5S rRNA primary transcript binding.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: RNA processing.
4 alleles are reported.
The phenotypes of these alleles are annotated with: midgut constriction 2; trichogen cell; midgut constriction; midgut constriction 1; midgut constriction 3.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Lupus La protein; Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; RNA-binding motif; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in adult female stages.