Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name lark
Flybase description The gene lark is referred to in FlyBase by the symbol Dmel\lark (CG8597, FBgn0011640).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.4118 1.5139 0.527524 -0.3461 -1.311273 -0.6762 -1.49322 -0.400664
    Affimetrix absolute value 7.923 8.215 8.413 8.367 8.401 8.201 7.981 8.157
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: mRNA binding.
There is experimental evidence that it is involved in the biological process: protein localization; actin cytoskeleton organization; circadian rhythm; mitosis; negative regulation of eclosion; oogenesis; embryo development; eclosion rhythm; cytoplasmic transport, nurse cell to oocyte.
29 alleles are reported.
The phenotypes of these alleles are annotated with: adult cuticle; scutellar bristle; wing; posterior scutellar bristle.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; Zinc finger, CCHC retroviral-type; Zinc finger, CCHC-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-12 hour embryonic stages.