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|Flybase description||The gene Mothers against dpp is referred to in FlyBase by the symbol Dmel\Mad (CG12399, FBgn0011648).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding.
There is experimental evidence for 16 unique biological process terms, many of which group under: anatomical structure development; biological regulation; regulation of developmental process; post-embryonic organ morphogenesis; post-embryonic appendage morphogenesis; cellular process involved in reproduction; organ morphogenesis; multicellular organismal reproductive process; trunk segmentation; regulation of cellular macromolecule biosynthetic process; regulation of S phase of mitotic cell cycle; sensory organ development; regulation of multicellular organismal development.
83 alleles are reported.
The phenotypes of these alleles are annotated with 40 unique terms, many of which group under: organ system; adult segment; organ system subdivision; adult mesothoracic segment; nervous system; embryonic/larval tracheal system; germarium; synapse; somatic cell; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Dwarfin; MAD homology 1, Dwarfin-type; MAD homology, MH1; SMAD domain, Dwarfin-type; SMAD domain-like; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis.