Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Med
Flybase description The gene Medea is referred to in FlyBase by the symbol Dmel\Med (CG1775, FBgn0011655).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -20.4338 -12.8103 -14.615274 -18.5741 -29.521434 -25.4339 -23.83843 -18.971962
    Affimetrix absolute value 4.06 3.958 4.323 4.182 3.903 3.897 3.981 4.027
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding.
There is experimental evidence for 13 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular process involved in reproduction; regulation of developmental process; post-embryonic appendage morphogenesis; regionalization; multicellular organismal reproductive process; post-embryonic organ morphogenesis; cell proliferation; cellular component organization or biogenesis; dorsal/ventral axis specification.
52 alleles are reported.
The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system; organ system subdivision; adult segment; nervous system; germarium; synapse; adult mesothoracic segment; appendage segment; somatic cell; thoracic segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Dwarfin; MAD homology 1, Dwarfin-type; MAD homology, MH1; SMAD domain, Dwarfin-type; SMAD domain-like; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.