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|Flybase description||The gene Moesin is referred to in FlyBase by the symbol Dmel\Moe (CG10701, FBgn0011661).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: determination of left/right symmetry; olfactory behavior; oocyte anterior/posterior axis specification; actin cytoskeleton organization; establishment or maintenance of epithelial cell apical/basal polarity; establishment or maintenance of polarity of larval imaginal disc epithelium; rhabdomere membrane biogenesis; rhabdomere development; regulation of actin cytoskeleton organization; regulation of membrane potential in photoreceptor cell.
93 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; organ system; non-connected developing system; primordium; thoracic segment; nervous system; imaginal precursor; dorsal trunk primordium; organelle; embryonic hindgut; somatic cell; somatic stem cell; dorsal thoracic disc; external compound sense organ; embryonic foregut.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Band 4.
1 domain; Band 4.
1 family; Ezrin/radixin/moesin; Ezrin/radixin/moesin family; Ezrin/radixin/moesin, C-terminal; FERM central domain; FERM conserved site; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; Moesin; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult female stages.