Flygut: an atlas of the Drosophila adult midgut

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Gene name Moe
Flybase description The gene Moesin is referred to in FlyBase by the symbol Dmel\Moe (CG10701, FBgn0011661).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 6.6201 21.2149 13.750439 11.8848 5.406974 8.6516 9.61395 9.522566
    Affimetrix absolute value 11.12 12.024 11.926 11.949 11.164 11.653 11.807 11.441
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: determination of left/right symmetry; olfactory behavior; oocyte anterior/posterior axis specification; actin cytoskeleton organization; establishment or maintenance of epithelial cell apical/basal polarity; establishment or maintenance of polarity of larval imaginal disc epithelium; rhabdomere membrane biogenesis; rhabdomere development; regulation of actin cytoskeleton organization; regulation of membrane potential in photoreceptor cell.
93 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; organ system; non-connected developing system; primordium; thoracic segment; nervous system; imaginal precursor; dorsal trunk primordium; organelle; embryonic hindgut; somatic cell; somatic stem cell; dorsal thoracic disc; external compound sense organ; embryonic foregut.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Band 4.
1 domain; Band 4.
1 family; Ezrin/radixin/moesin; Ezrin/radixin/moesin family; Ezrin/radixin/moesin, C-terminal; FERM central domain; FERM conserved site; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; Moesin; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult female stages.