Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pdh
Flybase description The gene Photoreceptor dehydrogenase is referred to in FlyBase by the symbol Dmel\Pdh (CG4899, FBgn0011693).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -28.755 -16.7776 -23.117799 -25.7017 -35.615564 -38.4657 -26.7967 -24.91521
    Affimetrix absolute value 3.566 3.573 3.685 3.708 3.619 3.305 3.807 3.66
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: retinol dehydrogenase activity.
There is experimental evidence that it is involved in the biological process: retinol metabolic process; retinal metabolic process; phagocytosis, engulfment.
9 alleles are reported.
The phenotype of these alleles is annotated with: rhabdomere.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Alcohol dehydrogenase, insect-type; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed during late pupal stages, in adult male stages.