Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name byn
Flybase description The gene brachyenteron is referred to in FlyBase by the symbol Dmel\byn (CG7260, FBgn0011723).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -33.3033 -22.9323 -38.100185 -43.131 -56.880855 -32.4289 1.36554 -25.266359
    Affimetrix absolute value 3.352 3.108 2.942 2.971 2.93 3.551 8.917 3.608
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; DNA binding.
There is experimental evidence that it is involved in the biological process: hindgut morphogenesis; Malpighian tubule morphogenesis; midgut development.
14 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; primordium; midgut constriction; non-connected developing system; portion of tissue; somatic cell; extended germ band embryo; hypodermal muscle of larval abdomen; embryonic hindgut; adult specialised Malpighian tubule cell; female germline cyst; circular visceral muscle fiber; organ system subdivision; ectoderm derivative; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Transcription factor, Brachyury; Transcription factor, T-box; Transcription factor, T-box, conserved site; p53-like transcription factor, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.