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|Flybase description||The gene twinstar is referred to in FlyBase by the symbol Dmel\tsr (CG4254, FBgn0011726).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin binding.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; sensory organ development; establishment of planar polarity; cell division; biological regulation; cellular process involved in reproduction; leg morphogenesis; regulation of cellular component organization; protein complex biogenesis; central nervous system development; female gonad development; actin filament-based process.
49 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; adult segment; sensillum; external compound sense organ; organ system; cytoplasmic part; cell cycle; cell projection; M phase of meiotic cell cycle; spermatocyte; actomyosin contractile ring; meiosis II; cell projection membrane; wing hair; imaginal precursor; adult cuticle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Actin-binding, cofilin/tropomyosin type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.