Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tsr
Flybase description The gene twinstar is referred to in FlyBase by the symbol Dmel\tsr (CG4254, FBgn0011726).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 26.6512 35.9292 30.964066 29.9406 20.996343 31.0607 14.56099 29.64748
    Affimetrix absolute value 13.134 12.775 13.123 13.286 13.143 13.518 12.401 13.097
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin binding.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; sensory organ development; establishment of planar polarity; cell division; biological regulation; cellular process involved in reproduction; leg morphogenesis; regulation of cellular component organization; protein complex biogenesis; central nervous system development; female gonad development; actin filament-based process.
49 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; adult segment; sensillum; external compound sense organ; organ system; cytoplasmic part; cell cycle; cell projection; M phase of meiotic cell cycle; spermatocyte; actomyosin contractile ring; meiosis II; cell projection membrane; wing hair; imaginal precursor; adult cuticle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Actin-binding, cofilin/tropomyosin type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.