Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name wee
Flybase description The gene wee is referred to in FlyBase by the symbol Dmel\wee (CG4488, FBgn0011737).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.3258 -6.8243 -17.449912 -11.5705 -29.428462 -14.1718 -13.33005 -23.426748
    Affimetrix absolute value 4.788 4.854 4.074 4.882 3.919 4.775 4.841 3.753
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein tyrosine kinase activity.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle, embryonic; centrosome localization; centrosome separation; negative regulation of cyclin-dependent protein kinase activity; mitotic cell cycle checkpoint; nuclear division; spindle assembly; cell cycle.
15 alleles are reported.
The phenotypes of these alleles are annotated with: wing margin; interommatidial bristle; mitotic cell cycle; adult thorax; wing; ommatidium; scutellum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase-like domain; Wee1-like protein kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.