Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ctp
Flybase description The gene cut up is referred to in FlyBase by the symbol Dmel\ctp (CG6998, FBgn0011760).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.6997 5.7279 3.500095 5.6889 2.212779 4.3183 4.13973 3.4985
    Affimetrix absolute value 10.62 10.12 9.95 10.891 9.845 10.67 10.575 9.938
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: dynein intermediate chain binding; protein binding; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: actin filament bundle assembly; sperm individualization; bristle morphogenesis; imaginal disc-derived wing morphogenesis; autophagy; salivary gland cell autophagic cell death; spermatid nucleus elongation; neurogenesis; spermatogenesis.
53 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; sensillum; organ system subdivision; multicellular structure; sense organ; eo support cell; adult segment; multi-cell-component structure; adult mesothoracic segment; spermatocyte; spermatozoon; female germline cyst; commissure.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Dynein light chain, type 1/2; Dynein light chain, type 1/2, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.