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|Flybase description||The gene cut up is referred to in FlyBase by the symbol Dmel\ctp (CG6998, FBgn0011760).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: dynein intermediate chain binding; protein binding; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: actin filament bundle assembly; sperm individualization; bristle morphogenesis; imaginal disc-derived wing morphogenesis; autophagy; salivary gland cell autophagic cell death; spermatid nucleus elongation; neurogenesis; spermatogenesis.
53 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; sensillum; organ system subdivision; multicellular structure; sense organ; eo support cell; adult segment; multi-cell-component structure; adult mesothoracic segment; spermatocyte; spermatozoon; female germline cyst; commissure.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Dynein light chain, type 1/2; Dynein light chain, type 1/2, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.