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|Flybase description||The gene DP transcription factor is referred to in FlyBase by the symbol Dmel\Dp (CG4654, FBgn0011763).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; DNA binding.
There is experimental evidence that it is involved in the biological process: positive regulation of gene expression; positive regulation of nurse cell apoptosis; oogenesis; dorsal/ventral axis specification, ovarian follicular epithelium; regulation of cell cycle; cell cycle; DNA damage response, signal transduction resulting in induction of apoptosis.
38 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; organ system; external compound sense organ; adult segment; female germline cyst; sensillum; nervous system; eo support cell; nucleus; egg; cell cycle; imaginal precursor.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Transcription factor DP; Transcription factor DP, C-terminal; Transcription factor DP, subgroup; Transcription factor E2F/dimerisation partner (TDP); Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.