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|Flybase description||The gene E2F transcription factor is referred to in FlyBase by the symbol Dmel\E2f (CG6376, FBgn0011766).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; DNA binding.
There is experimental evidence that it is involved in the biological process: positive regulation of gene expression; cellular process; dendrite morphogenesis; neuron development; positive regulation of nurse cell apoptosis; muscle tissue development; antimicrobial humoral response; regulation of cell cycle; DNA endoreduplication.
77 alleles are reported.
The phenotypes of these alleles are annotated with 37 unique terms, many of which group under: organ system subdivision; external compound sense organ; primordium; adult segment; organ system; female germline cyst; egg; nervous system; imaginal precursor; adult mesothoracic segment.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: E2F Family; Transcription factor E2F/dimerisation partner (TDP); Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.