Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Ret
Flybase description The gene Ret oncogene is referred to in FlyBase by the symbol Dmel\Ret (CG14396, FBgn0011829).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -63.6627 -33.1362 -53.388111 -56.9504 -83.611819 -63.4621 -75.40975 -64.306141
    Affimetrix absolute value 2.421 2.582 2.444 2.567 2.378 2.575 2.325 2.285
    Affymetric present call in "x" number of chips 0 1 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: transmembrane receptor protein tyrosine kinase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: protein phosphorylation; signal transduction.
14 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; trichogen cell; cone cell; ommatidium.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-12 hour embryonic stages.