Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ance
Flybase description The gene Angiotensin converting enzyme is referred to in FlyBase by the symbol Dmel\Ance (CG8827, FBgn0012037).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.4359 14.5431 13.422559 1.3164 12.779694 13.3386 -3.7298 12.288291
    Affimetrix absolute value 5.778 11.464 11.921 8.773 12.429 12.283 6.978 11.83
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: peptidyl-dipeptidase activity.
There is experimental evidence that it is involved in the biological process: spermatid nucleus differentiation; sperm individualization; metamorphosis; response to symbiotic bacterium.
6 alleles are reported.
The phenotypes of these alleles are annotated with: major mitochondrial derivative; spermatid; testis; primary spermatocyte cyst; minor mitochondrial derivative.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Peptidase M2, peptidyl-dipeptidase A.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.