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|Flybase description||The gene Calpain-A is referred to in FlyBase by the symbol Dmel\CalpA (CG7563, FBgn0012051).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: calcium-dependent cysteine-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: dorsal/ventral pattern formation; BMP signaling pathway involved in spinal cord dorsal/ventral patterning; cuticle development; phagocytosis, engulfment.
9 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain; Peptidase C2, calpain family; Peptidase C2, calpain, catalytic domain; Peptidase C2, calpain, domain III; Peptidase C2, calpain, large subunit, domain III; Peptidase, cysteine peptidase active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages.