Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Trl
Flybase description The gene Trithorax-like is referred to in FlyBase by the symbol Dmel\Trl (CG33261, FBgn0013263).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.5116 -2.1826 -18.586109 -34.2552 -46.904347 -34.0047 -14.76607 -20.930345
    Affimetrix absolute value 3.797 6.512 3.969 3.3 3.228 3.48 4.761 3.869
    Affymetric present call in "x" number of chips 2 3 3 0 0 2 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; protein binding; DNA binding.
There is experimental evidence that it is involved in the biological process: cellular process; dosage compensation; nuclear division; syncytial blastoderm mitotic cell cycle; imaginal disc-derived wing morphogenesis; protein oligomerization.
69 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; egg; adult segment; eo support cell; female germline cyst; acellular anatomical structure; multicellular structure; imaginal precursor; external compound sense organ; chromatin.
It has 9 annotated transcripts and 9 annotated polypeptides.
Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding; Zinc finger, GAGA-binding factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages.
This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.
The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.