Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Odc1
Flybase description The gene Ornithine decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Odc1 (CG8721, FBgn0013307).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.781 -21.3588 -31.421801 -30.1032 -30.291056 -30.8582 -4.56115 -15.232228
    Affimetrix absolute value 4.146 3.217 3.21 3.478 3.851 3.62 6.476 4.342
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ornithine decarboxylase activity.
It is reported to be involved in the biological process: polyamine biosynthetic process.
2 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Alanine racemase/group IV decarboxylase, C-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, conserved site; Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site; Ornithine decarboxylase; Ornithine/DAP/Arg decarboxylase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages.