Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name not
Flybase description The gene non-stop is referred to in FlyBase by the symbol Dmel\not (CG4166, FBgn0013717).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.9184 -3.8436 -4.918006 -5.3648 -5.499471 -6.1392 -7.4441 -5.662983
    Affimetrix absolute value 5.856 5.695 5.896 5.972 6.305 5.949 5.681 5.749
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: protein deubiquitination; histone deubiquitination; chromatin organization; regulation of transcription, DNA-dependent; axon guidance; glial cell migration; glial cell development; axon target recognition; ubiquitin-dependent protein catabolic process.
30 alleles are reported.
The phenotypes of these alleles are annotated with: medulla neuropil glial cell; epithelial glial cell; medulla; lamina; lamina plexus; marginal glial cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2; Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site; Zinc finger, C2H2-like; Zinc finger, RING/FYVE/PHD-type; Zinc finger, UBP-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.