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|Flybase description||The gene non-stop is referred to in FlyBase by the symbol Dmel\not (CG4166, FBgn0013717).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: protein deubiquitination; histone deubiquitination; chromatin organization; regulation of transcription, DNA-dependent; axon guidance; glial cell migration; glial cell development; axon target recognition; ubiquitin-dependent protein catabolic process.
30 alleles are reported.
The phenotypes of these alleles are annotated with: medulla neuropil glial cell; epithelial glial cell; medulla; lamina; lamina plexus; marginal glial cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2; Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site; Zinc finger, C2H2-like; Zinc finger, RING/FYVE/PHD-type; Zinc finger, UBP-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.