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|Flybase description||The gene short stop is referred to in FlyBase by the symbol Dmel\shot (CG18076, FBgn0013733).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: negative regulation of microtubule depolymerization; dendrite morphogenesis; oocyte fate determination; regulation of axon extension; microtubule cytoskeleton organization; mushroom body development; open tracheal system development; branch fusion, open tracheal system; lumen formation, open tracheal system; axon midline choice point recognition.
79 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system subdivision; organ system; late extended germ band embryo; multi-cell-component structure; primordium; ectoderm derivative; embryonic/larval neuron; integumentary specialisation; portion of tissue; presumptive embryonic/larval nervous system.
It has 22 annotated transcripts and 22 annotated polypeptides.
Protein features are: Actinin-type, actin-binding, conserved site; Calcium-binding EF-hand; Calponin homology domain; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain; Growth-arrest-specific protein 2 domain; Plectin repeat; Spectrin repeat; Spectrin/alpha-actinin; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages.