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|Flybase description||The gene alien is referred to in FlyBase by the symbol Dmel\alien (CG9556, FBgn0013746).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; nuclear hormone receptor binding; ligand-dependent nuclear receptor binding; protein homodimerization activity; transcription corepressor activity.
There is experimental evidence that it is involved in the biological process: protein stabilization; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of transcription, DNA-dependent; neurogenesis; phagocytosis, engulfment.
3 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: PCI/PINT associated module; Proteasome component (PCI) domain; Tetratricopeptide-like helical; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.