Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Awh
Flybase description The gene Arrowhead is referred to in FlyBase by the symbol Dmel\Awh (CG1072, FBgn0013751).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -38.1055 -23.1559 -42.089904 -41.8363 -57.442045 -48.4075 -38.70907 -40.151382
    Affimetrix absolute value 3.173 3.113 2.814 3.002 2.924 2.976 3.277 2.952
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: imaginal disc development.
37 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; adult segment; organ system; thoracic segment; sensillum; appendage segment; imaginal precursor; anterior vertical bristle; salivary gland imaginal ring; organelle; larval abdominal segment; dorsal thoracic disc; spiracle; external compound sense organ.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeodomain-like; Homeodomain-related; Zinc finger, LIM-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-18 hour embryonic stages.