Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Cp1
Flybase description The gene Cysteine proteinase-1 is referred to in FlyBase by the symbol Dmel\Cp1 (CG6692, FBgn0013770).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 9.5034 20.4404 14.627812 7.5901 10.566944 12.2054 10.53117 13.03319
    Affimetrix absolute value 11.656 11.964 12.037 11.277 12.147 12.155 11.908 11.938
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: cysteine-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: autophagic cell death; salivary gland cell autophagic cell death.
34 alleles are reported.
The phenotypes of these alleles are annotated with: egg; adult abdominal segment 3; adult abdominal segment 1; adult abdominal segment 5; wing; adult abdominal segment 2; adult abdominal segment 4.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Peptidase C1A, papain; Peptidase C1A, papain C-terminal; Peptidase, cysteine peptidase active site; Proteinase inhibitor I29, cathepsin propeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.