Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Deaf1
Flybase description The gene Deformed epidermal autoregulatory factor-1 is referred to in FlyBase by the symbol Dmel\Deaf1 (CG8567, FBgn0013799).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.8527 -9.1407 -15.160429 -13.3125 -18.89081 -16.7793 -18.81546 -18.064276
    Affimetrix absolute value 4.112 4.447 4.325 4.677 4.538 4.505 4.339 4.081
    Affymetric present call in "x" number of chips 0 3 2 3 1 2 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: regulation of immune response; embryo development ending in birth or egg hatching; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent.
9 alleles are reported.
The phenotypes of these alleles are annotated with: wing vein L3; eye; macrochaeta; scutellar bristle; wing; ommatidium; mesothoracic bristle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: SAND domain; SAND domain-like; Transcription factor DEAF-1; Zinc finger, MYND-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages.