Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Rab5
Flybase description The gene Rab-protein 5 is referred to in FlyBase by the symbol Dmel\Rab5 (CG3664, FBgn0014010).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.079 2.8574 1.333398 2.8118 0.354807 1.4961 3.54758 0.731996
    Affimetrix absolute value 9.455 9.107 8.58 9.876 8.785 9.14 10.37 8.664
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence for 16 unique biological process terms, many of which group under: cellular component organization or biogenesis; localization; biological regulation; cell cycle; neuron differentiation; membrane organization; synaptic transmission; multicellular organism reproduction; organelle organization; cell cycle process; neuron projection development.
45 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; multicellular structure; portion of tissue; cytoplasmic part; organelle; cell part; organ system subdivision; thoracic segment; epithelial cell; synapse.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rab type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed during late larval stages, during early pupal stages.