Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name bif
Flybase description The gene bifocal is referred to in FlyBase by the symbol Dmel\bif (CG1822, FBgn0014133).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.9573 1.7783 1.797165 3.7392 1.275497 1.6184 -3.69066 0.887719
    Affimetrix absolute value 6.847 8.442 8.997 10.271 9.09 9.245 6.704 8.813
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin binding; actin filament binding; microtubule binding.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; negative regulation of axon extension; axon guidance.
32 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system subdivision; organ system; external compound sense organ; adult segment; adult; larval head segment; organelle; actin cytoskeleton; rhabdomere; cell part.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Carbohydrate-binding domain family 9-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.