Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name gcm
Flybase description The gene glial cells missing is referred to in FlyBase by the symbol Dmel\gcm (CG12245, FBgn0014179).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -52.7678 -34.4028 -44.869758 -54.6287 -72.015589 -65.1972 -62.93519 -51.255862
    Affimetrix absolute value 2.697 2.534 2.693 2.632 2.596 2.535 2.585 2.59
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA binding.
There is experimental evidence for 13 unique biological process terms, many of which group under: system development; glial cell differentiation; biological regulation; cellular process; regulation of developmental process; neuron differentiation; immune system process; cell proliferation; cellular component organization or biogenesis; establishment of blood-brain barrier; cell fate commitment; hemopoietic or lymphoid organ development.
54 alleles are reported.
The phenotypes of these alleles are annotated with 60 unique terms, many of which group under: organ system; organ system subdivision; multicellular structure; non-connected developing system; larval abdominal segment; embryonic/larval neuron; peripheral nervous system; portion of tissue; embryonic/larval hemocoel; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Transcription regulator, GCM-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 00-18 hour embryonic stages.