Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name mirr
Flybase description The gene mirror is referred to in FlyBase by the symbol Dmel\mirr (CG10601, FBgn0014343).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.072 -4.0204 -16.35341 -21.2799 -29.608207 -28.5566 -28.67004 -15.537047
    Affimetrix absolute value 3.825 5.611 4.184 3.977 3.887 3.728 3.723 4.336
    Affymetric present call in "x" number of chips 0 3 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; embryonic development via the syncytial blastoderm; equator specification; imaginal disc-derived wing morphogenesis; dorsal appendage formation; compound eye morphogenesis; peripheral nervous system development.
36 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system subdivision; organ system; acellular anatomical structure; postalar bristle; imaginal precursor; integumentary plate; thoracic segment; eo support cell; cell part; larval head segment; external compound sense organ.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeobox KN domain; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Iroquois-class homeodomain protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.