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|Flybase description||The gene Casein kinase Iα is referred to in FlyBase by the symbol Dmel\CkIα (CG2028, FBgn0015024).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein kinase activity.
There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; regulation of Wnt receptor signaling pathway; DNA repair; protein phosphorylation; negative regulation of smoothened signaling pathway; neurogenesis; phagocytosis, engulfment.
27 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; ventral nerve cord commissure; eye; embryonic epidermis; longitudinal connective.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages.