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|Flybase description||The gene Eukaryotic initiation factor 4E is referred to in FlyBase by the symbol Dmel\eIF-4E (CG4035, FBgn0015218).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: translation initiation factor activity; protein binding; eukaryotic initiation factor 4G binding; RNA cap binding; RNA 7-methylguanosine cap binding.
There is experimental evidence for 14 unique biological process terms, many of which group under: cellular component organization or biogenesis; cell cycle; cell cycle process; gene expression; programmed cell death; organelle organization; primary metabolic process; cellular macromolecule biosynthetic process; cellular biosynthetic process; gland morphogenesis; biological regulation; cell death.
40 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; peripheral nervous system; external compound sense organ; thoracic segment; multicellular structure; cell cycle; synapse; epithelial furrow; adult segment.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: Eukaryotic translation initiation factor 4E (eIF-4E), conserved site; Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.