|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene Inhibitor of apoptosis 2 is referred to in FlyBase by the symbol Dmel\Iap2 (CG8293, FBgn0015247).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding.
There is experimental evidence that it is involved in the biological process: positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; anti-apoptosis; negative regulation of caspase activity; sensory organ development; negative regulation of apoptosis; defense response to Gram-negative bacterium; peptidoglycan recognition protein signaling pathway; regulation of caspase activity; positive regulation of protein import into nucleus, translocation.
31 alleles are reported.
The phenotypes of these alleles are annotated with: wing disc; trichogen cell; mesothoracic tergum; pigment cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Baculoviral inhibition of apoptosis protein repeat; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.