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|Flybase description||The gene Phosphotidylinositol 3 kinase 59F is referred to in FlyBase by the symbol Dmel\Pi3K59F (CG5373, FBgn0015277).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 1-phosphatidylinositol-3-kinase activity.
There is experimental evidence that it is involved in the biological process: dsRNA transport; endocytosis; phosphatidylinositol phosphorylation; cellular response to starvation; autophagic vacuole assembly; regulation of autophagy.
13 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-type fold; C2 calcium/lipid-binding domain, CaLB; Phosphatidylinositol 3-/4-kinase, catalytic; Phosphatidylinositol 3-kinase, Vps34 type; Phosphatidylinositol 3/4-kinase, conserved site; Phosphatidylinositol Kinase; Phosphoinositide 3-kinase, C2; Phosphoinositide 3-kinase, accessory (PIK) domain; Protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.