Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Pi3K59F
Flybase description The gene Phosphotidylinositol 3 kinase 59F is referred to in FlyBase by the symbol Dmel\Pi3K59F (CG5373, FBgn0015277).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.008 -5.6459 -5.65352 -6.9662 -7.329279 -7.743 -6.93431 -7.040983
    Affimetrix absolute value 5.415 5.142 5.684 5.623 5.895 5.638 5.812 5.447
    Affymetric present call in "x" number of chips 1 1 1 1 2 1 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 1-phosphatidylinositol-3-kinase activity.
There is experimental evidence that it is involved in the biological process: dsRNA transport; endocytosis; phosphatidylinositol phosphorylation; cellular response to starvation; autophagic vacuole assembly; regulation of autophagy.
13 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-type fold; C2 calcium/lipid-binding domain, CaLB; Phosphatidylinositol 3-/4-kinase, catalytic; Phosphatidylinositol 3-kinase, Vps34 type; Phosphatidylinositol 3/4-kinase, conserved site; Phosphatidylinositol Kinase; Phosphoinositide 3-kinase, C2; Phosphoinositide 3-kinase, accessory (PIK) domain; Protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.