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|Flybase description||The gene derailed is referred to in FlyBase by the symbol Dmel\drl (CG17348, FBgn0015380).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Wnt-protein binding.
There is experimental evidence that it is involved in the biological process: olfactory learning; axon guidance; learning or memory; memory; haltere development; signal transduction; muscle attachment; salivary gland morphogenesis; axon midline choice point recognition.
36 alleles are reported.
The phenotypes of these alleles are annotated with 56 unique terms, many of which group under: organ system subdivision; hypodermal muscle of larval abdomen; organ system; A1-7 transverse muscle; adult segment; non-connected developing system; abdominal 1 transverse muscle; cell body; abdominal 2 lateral transverse muscle 2; embryonic foregut.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; WIF domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages.