Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name jumu
Flybase description The gene jumeau is referred to in FlyBase by the symbol Dmel\jumu (CG4029, FBgn0015396).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -40.248 -19.3753 -34.100336 -32.155 -41.44237 -15.452 -53.87085 -32.654557
    Affimetrix absolute value 3.079 3.349 3.104 3.383 3.482 4.625 2.815 3.228
    Affymetric present call in "x" number of chips 0 2 0 1 1 3 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: nucleolus organization; chromatin organization; neuroblast fate determination; compound eye development; dendrite morphogenesis; neuron development; asymmetric protein localization; muscle organ development; imaginal disc-derived wing morphogenesis.
42 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; organ system; adult segment; organelle; external compound sense organ; thoracic segment; intracellular non-membrane-bounded organelle; intracellular organelle part; nuclear part; embryonic/larval neuron.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.