Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name kek1
Flybase description The gene kekkon-1 is referred to in FlyBase by the symbol Dmel\kek1 (CG12283, FBgn0015399).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -47.8648 -25.597 -34.187332 -45.1512 -55.345895 -55.145 -54.81555 -38.795635
    Affimetrix absolute value 2.855 2.989 3.126 2.891 2.97 2.783 2.787 3.005
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: epidermal growth factor binding.
There is experimental evidence that it is involved in the biological process: negative regulation of epidermal growth factor receptor signaling pathway; cytokinesis; oogenesis; neurogenesis.
42 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; adult segment; thoracic segment; external compound sense organ; adult; cell part; cell periphery; egg; epithelial cell; cell; peripheral nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cysteine-rich flanking region, C-terminal domain; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Leucine-rich repeat; Leucine-rich repeat, typical subtype.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during early pupal stages.