Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Rme-8
Flybase description The gene Receptor mediated endocytosis 8 is referred to in FlyBase by the symbol Dmel\Rme-8 (CG8014, FBgn0015477).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.7294 -1.1629 -2.16568 -1.856 -4.442185 -2.5012 -3.66047 -3.641682
    Affimetrix absolute value 5.463 7.411 7.086 7.519 6.646 7.248 6.714 6.461
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: heat shock protein binding.
There is experimental evidence that it is involved in the biological process: border follicle cell migration; receptor-mediated endocytosis.
25 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-like helical; Armadillo-type fold; Heat shock protein DnaJ, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.