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|Flybase description||The gene APC-like is referred to in FlyBase by the symbol Dmel\Apc (CG1451, FBgn0015589).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: beta-catenin binding.
There is experimental evidence for 13 unique biological process terms, many of which group under: system development; biological regulation; multicellular organismal development; cellular component organization or biogenesis; cellular process; regulation of Wnt receptor signaling pathway; cell proliferation; larval chitin-based cuticle development; localization; embryonic development via the syncytial blastoderm.
14 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; organ system; histaminergic neuron; adult; multi-tissue structure; male organism; region of integument; somatic cell of testis.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Adenomatous polyposis coli protein, 15 residue repeat; Adenomatous polyposis coli protein, cysteine-rich repeat; Armadillo; Armadillo-like helical; Armadillo-type fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period.