Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CadN
Flybase description The gene Cadherin-N is referred to in FlyBase by the symbol Dmel\CadN (CG7100, FBgn0015609).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.0521 -13.9961 -18.154703 -21.0421 -23.614412 -21.7828 -21.6637 -16.949218
    Affimetrix absolute value 4.328 3.821 4.005 3.993 4.202 4.119 4.117 4.168
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: receptor activity; cell adhesion molecule binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: cellular component organization or biogenesis; neuron differentiation; sensory organ development; biological regulation; compound eye photoreceptor development; growth; regulation of neurogenesis; neuron projection development; cell adhesion; developmental growth.
42 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; organ system; adult segment; embryonic/larval neuron; external compound sense organ; non-connected developing system; peripheral nervous system; imaginal precursor; MP1 neuron; histaminergic neuron; integumentary plate.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Cadherin; Cadherin conserved site; Cadherin-like; Concanavalin A-like lectin/glucanase; Concanavalin A-like lectin/glucanase, subgroup; EGF; EGF-like calcium-binding; EGF-like region, conserved site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Laminin G domain; Laminin G, subdomain 2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period.