Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Dref
Flybase description The gene DNA replication-related element factor is referred to in FlyBase by the symbol Dmel\Dref (CG5838, FBgn0015664).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.3458 -3.0082 -4.050303 -3.4173 -6.043813 -3.642 -4.55039 -5.515048
    Affimetrix absolute value 6.339 6.045 6.2 6.621 6.191 6.697 6.375 5.902
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; sensory organ development; system development; multicellular organismal development; cell cycle; cell cycle process; cellular process; regulation of macromolecule biosynthetic process; anatomical structure development; cellular component organization or biogenesis.
21 alleles are reported.
The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; organ system; integumentary plate; thoracic segment; eo support cell; peripheral nervous system; nucleus; organelle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Ribonuclease H-like; Zinc finger, BED-type predicted.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.