Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Rbf
Flybase description The gene Retinoblastoma-family protein is referred to in FlyBase by the symbol Dmel\Rbf (CG7413, FBgn0015799).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.3238 -5.1004 -7.535621 -9.8495 -15.246216 -11.1256 -14.04069 -14.383806
    Affimetrix absolute value 4.232 5.279 5.278 5.126 4.889 5.109 4.766 4.494
    Affymetric present call in "x" number of chips 0 3 3 3 2 3 2 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transcription factor binding; transcription regulatory region DNA binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; cell cycle; cell cycle process; negative regulation of cellular biosynthetic process; regulation of apoptosis; negative regulation of metabolic process; negative regulation of biosynthetic process; interphase of mitotic cell cycle; regulation of S phase of mitotic cell cycle; regulation of DNA binding.
58 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; adult segment; organ system; external compound sense organ; thoracic segment; integumentary plate; cell part; non-connected developing system; cell cycle; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cyclin-like; Retinoblastoma-associated protein, A-box; Retinoblastoma-associated protein, B-box.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.