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|Flybase description||The gene Retinoblastoma-family protein is referred to in FlyBase by the symbol Dmel\Rbf (CG7413, FBgn0015799).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transcription factor binding; transcription regulatory region DNA binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; cell cycle; cell cycle process; negative regulation of cellular biosynthetic process; regulation of apoptosis; negative regulation of metabolic process; negative regulation of biosynthetic process; interphase of mitotic cell cycle; regulation of S phase of mitotic cell cycle; regulation of DNA binding.
58 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; adult segment; organ system; external compound sense organ; thoracic segment; integumentary plate; cell part; non-connected developing system; cell cycle; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cyclin-like; Retinoblastoma-associated protein, A-box; Retinoblastoma-associated protein, B-box.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.