Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name apt
Flybase description The gene apontic is referred to in FlyBase by the symbol Dmel\apt (CG5393, FBgn0015903).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.5654 -9.0572 -10.988598 -3.653 -17.344826 -10.7874 -12.20865 -12.290546
    Affimetrix absolute value 4.224 4.457 4.765 6.526 4.72 5.131 4.948 4.709
    Affymetric present call in "x" number of chips 0 1 1 3 0 1 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; protein binding; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: central nervous system development; neuromuscular synaptic transmission; positive regulation of transcription from RNA polymerase II promoter; open tracheal system development.
65 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; adult segment; non-connected developing system; synapse; multicellular structure; pharyngeal sclerite; portion of tissue; peripheral nervous system.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: SANT domain, DNA binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis.