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|Flybase description||The gene apontic is referred to in FlyBase by the symbol Dmel\apt (CG5393, FBgn0015903).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; protein binding; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: central nervous system development; neuromuscular synaptic transmission; positive regulation of transcription from RNA polymerase II promoter; open tracheal system development.
65 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; adult segment; non-connected developing system; synapse; multicellular structure; pharyngeal sclerite; portion of tissue; peripheral nervous system.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: SANT domain, DNA binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis.